Novel norhumulene and xeniaphyllane-derived terpenoids from a formosan soft coral Sinularia gibberosa.
نویسندگان
چکیده
A novel skeletal norhumulene (1) and six xeniaphyllane-derived compounds, including norditerpenoids (2, 3) and diterpenoids (4-7), were isolated from the EtOAc extract of the Formosan soft coral Sinularia gibberosa. Their structures were elucidated by spectroscopic analysis. In vitro cytotoxic evaluation of the above metabolites revealed that 2 and 4 showed weak cytotoxicity toward a few cancer cell lines.
منابع مشابه
Xeniaphyllane-Derived Terpenoids from Soft Coral Sinularia nanolobata
A novel tetranorditerpenoid, sinubatin A (1) (having an unprecedented carbon skeleton), a new norditerpenoid, sinubatin B (2) (a 4,5-epoxycaryophyllene possessing an unusual methylfuran moiety side chain), and a known diterpenoid, gibberosin J (3) were isolated from soft coral Sinulariananolobata. The structures of the new compounds were elucidated by extensive analysis of spectroscopic data.
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 57 2 شماره
صفحات -
تاریخ انتشار 2009